Objectives of the Lectures on Monday the 4th and Tuesday the 5th of April 2011.

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At the end of the two lectures, the student should be able to:

  • ·         Calculate the value of osmotic pressure

    ·         Describe and differentiates between voltage-gated and ligand-gated ion channels.

    ·         Cite and example of mechanically-gated ion channels.

    ·         Discuss the significance of ion channels.

    ·         Differentiate between diffusion and Equilibrium Potentials.

    ·         Use Nernst Equation to calculate the value of equilibrium potentials for Na+, K+, Ca2+ and Cl- ions for a nerve and muscle cell membranes.

    ·         Discuss the meaning of Resting membrane Potential.

    ·         Describe the ionic basis of resting membrane Potential

    ·         Explain the origin and generation of the resting membrane Potential

    ·         Sketch the graphical representation of an Action Potentials.

    ·         Understand the conductions to sodium and potassium ions in the course of action potential.

    ·         Discuss the generation of the action potential.

    ·         Explain the origin of repolarization of the action potential.

    ·         Describe the reason of hyperpolarization or the undershoot of the action potential.

    ·         Discuss the refractory periods.

    ·         Differentiate between absolute and relative refractory periods.

    ·         Discuss the propagation of the action potentials

    ·         Describe the series of events happening in synaptic transmission.

    ·         Precise the difference between a general synapse and a neuromuscular junction.

    ·         List the different types of synapses.

    ·         Draw graphs of EPSP and IPSP

    ·         Differentiate between spatial and temporal summations.

    ·         List and give the functions of at least 5 neurotransmitters.

    ·         Describe the structure of skeletal, smooth and cardiac muscle.

    ·         Differentiate between different types of troponins

    ·         Present the steps of excitation contraction coupling in smooth, cardiac and skeletal muscles.

    ·         Present the energy sources for muscle metabolism

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